It’s not all child’s play: Presurgical functional mapping in children using transcranial magnetic stimulation

Symposium title: Non-invasive brain stimulation in pediatric epilepsy: Diagnostic, biomarker, and therapeutic applications of TMS description: Many diagnostic approaches for epilepsy require invasive approaches. However, populations, non-invasive are preferred. Hence, centers have begun using the (NIBS) technique transcranial magnetic (TMS) functional, mapping eloquent cortex prior to surgery. few epileptologists familiar with broader scope clinical NIBS technology. The neurophysiologic principles behind make it a unique tool examining cortical/circuit excitability network connectivity that disrupted by syndromes. derived parameters cortical can quantify nature neuronal dysfunction, disease progression, responsiveness pharmacological nonpharmacological treatments. Concurrent EEG including direct current (tDCS) measure how alters connectivity. Finally, repetitive tDCS protocols alter excitability, thus providing novel, treatment. Speakers will review basic tDCS, exciting research these techniques define pathophysiology various symptoms, studies assessing effectiveness treatment refractory epilepsy, status epilepticus epilepsia partialis continua. Abstract This presentation symposium titled “Non-invasive Biomarker, Therapeutic TMS” utility as map children undergoing or tumor talk describe recent advances delivery catapulted its use presurgical functional mapping. In particular, focus on safety advantages children. speaker fundamentals navigated setting used motor Examples application measuring monitoring central conduction times induced plasticity also be presented. Next, language challenges function young surgery discussed. data indicating neurological disorders highlight child neurology practice presenting example case series population. present well results compare other methods. feasibility integrating into pre-operative evaluation risk-benefit decision making role plays managing tumor. Research Category Technology Methods Clinical Research: 10. Transcranial Magnetic Stimulation Keywords: Functional mapping, Pediatric TMS, Presurgical